Sigma 1 receptor linked to retina preservation

Written by Alice Weatherston

In a new study carried out at the Medical College of Georgia at Georgia Regents University (GA, USA) researchers have highlighted the potentially key role of a receptor, termed the sigma 1 receptor, in supporting the retina. The research, which was published recently in Free Radical Biology and Medicine, indicates a potential new treatment target for progressive retinal diseases. The team initially discovered that the removal of sigma 1 receptors from Müller cells in the eyes of knockout mice models was sufficient to significantly increase the levels of reactive oxygen species (ROS), indicating a direct link between the receptor and...

To view this content, please register now for access

It's completely free