Treating neurodegenerative disease with tyrosine kinase inhibitors

Background. Neurodegenerative diseases include genetic and sporadic disorders associated with progressive nervous system dysfunction. There is no cure for neurodegenerative diseases to date. Some symptomatic management medicines exist with limited efficacy, but they do not slow down or halt neurodegenerative processes. Alzheimer’s disease and Parkinson’s disease (PD) are the two most common neurodegenerative diseases affecting an estimated 6.8 million individuals in the U.S. [1]. More than 30 million people currently suffer from these diseases worldwide [2]. Aging is a critical risk factor associated with neurodegenerative diseases and the number of people over 75 years of age will double in the...