Could activating proteins that support cell motility actually impede glioblastoma spread?

The lethality of aggressive glioblastomas lies within their widespread ability to resist both surgery and chemoradiotherapy, and subsequently invade surrounding healthy tissue. A new laboratory study, published recently in Molecular Biology of the Cell, has presented details of a novel method of potentially preventing the cell migration associated with this invasive spread. The collaborative study, carried out by a team of investigators from both the University of Toledo Health Science Campus (OH, USA) and Van Andel Research Institute (MI, USA), built upon previous work carried out by the senior author Arthur Alberts (Van Andel Research Institute) in which he uncovered...