Original Publication Date: >12 November, 2015
Publication / Source: Future Neurology
Authors: Stuart D Portbury, Luz Fernanda Yévenes & Paul A Adlard
Zinc (Zn2+) is an essential metal in the brain, having critical roles in many proteins and cellular pathways, including synaptic plasticity and the normal functioning of long-term potentiation, the in vitro correlate of learning and memory. Importantly, several neurodegenerative diseases, such as Parkinson’s disease and Alzheimer’s disease, show alterations in Zn2+ metabolism that may be involved in the pathogenesis of these disorders.