Original Publication Date: >8 December, 2015
Publication / Source: Biomarkers in Medicine
Authors: Lucilla Parnetti, Claudia Cicognola, Paolo Eusebi & Davide Chiasserini
Since diagnosis of Parkinson’s disease (PD) is mostly based on clinical criteria, it is almost impossible to formulate an early diagnosis, as well as a timely differential diagnosis versus other parkinsonisms. A great effort in searching reliable biomarkers both for early diagnosis and prognosis in PD is currently ongoing. Cerebrospinal fluid has been widely investigated as potential source for such biomarkers, with particular emphasis on α-synuclein (α-syn) species.