Original Publication Date: >1 March, 2016
Publication / Source: Epigenomics
Authors: Zhiqin Wang, Beisha Tang, Yuquan He & Peng Jin
Neurogenesis is not limited to the embryonic stage, but continually proceeds in the adult brain throughout life. Epigenetic mechanisms, including DNA methylation, histone modification and noncoding RNA, play important roles in neurogenesis. For decades, DNA methylation was thought to be a stable modification, except for demethylation in the early embryo. In recent years, DNA methylation has proved to be dynamic during development.