Original Publication Date: >18 March, 2016
Publication / Source: Pain Management
Authors: Winfried Häuser, Frank Petzke, Lukas Radbruch & Thomas R Tölle
The rise of opioid prescriptions and associated deaths (‘opioid epidemic’) in North America has evoked worldwide discussions on the long-term efficacy and safety of long-term opioid therapy (LtOT) for chronic noncancer pain (CNCP). We discuss if the opioid epidemic is a real worldwide or a more North American phenomenon. We consider reasons of the opioid epidemic. We highlight differences in the appraisal of the evidence of recent systematic reviews on LtOT for CNCP of US and European authors.