New dietary influence identified in multiple sclerosis progression

Written by Lauren Pulling

Researchers from Brigham and Women’s Hospital (MA, USA) have suggested that neuroinflammation and neurodegeneration may be influenced by diet and gut flora composition. Their findings in mouse models of multiple sclerosis (MS) and patient samples indicate that gut bacteria may impact astrocyte activity and as a result affect disease progression. Previous research has indicated a link between brain inflammation and the gut microbiome; however, the nature of the relationship between the two has remained largely unknown. To address this issue, the research team, led by Francisco Quintana (Brigham and Women’s Hospital) carried out a genome-wide transcriptional analysis on astrocytes from...

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