Authors: Alice Weatherston
A new study has indicated a potential link between the extent of damage to the blood-brain barrier following stroke and the severity of bleeding following invasive stroke therapy. The findings are part of the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution (DEFUSE)-2 Study, which was developed in order to evaluate how MRIs may help to decide which patients should undergo endovascular therapy after ischemic stroke.
Brain scans of the more than 100 participants in the study were collected prior to endovascular therapy and within 12 hours of stroke onset. Utilizing a novel image processing method, study lead, Richard Leigh (National Institute of Health, National Institute of Neurological Disorders and Stroke; MD, USA) and his team were also able to obtain detailed measurements on the extent of blood-brain barrier damage following the stroke.