Neurology Central

Linking the brain and the gut – new insights for the control of obesity

Research presented at FENS (Federation of European Neurosciences Societies) Forum of Neuroscience (2–6 July 2016, Copenhagen, Denmark) earlier this week has highlighted a key relationship between two brain systems that are involved in eating behavior, including food intake and appetite control. The findings could have implications for the control of obesity, one of the most important current health issues.

Oleoylethanolamide (OEA) and histamine are widely known to influence food intake. High levels of histaminergic activity results in the suppression of food intake and OEA inhibits food intake by stimulating the production of oxytocin. Lead author of study presented at FENS, Beatrice Passani, and her team at the University of Florence (Italy) looked to investigate links between OEA, produced in the small intestine, and the brain’s histamine neurotransmitter system.

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