Neurology Central

Repurposing of malaria drug to halt ALS disease progression

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Researchers from the Hospital for Special Surgery (NY, USA) and other centres have discovered that pyrimethamine, a drug orignally used to treat malaria, lowers the levels of a biomarker linked to the inherited form of amyotrophic lateral sclerosis (ALS). The results, recently published in Annals of Neurology, suggest pyrimethamine could be useful in treating ALS.
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