Neurology Central

Alzheimer’s disease risk linked to gene network expressed in myeloid cells

Scientists from the Icahn School of Medicine at Mount Sinai (IL, USA) have identified a network of genes expressed by myeloid cells that are linked to late-onset Alzheimer’s disease (AD). The study, published in Nature Neuroscience, identified PU.1, a transcription factor vital for the development and function of myeloid cells, as a master regulator of this network of AD risk genes. Further research is necessary to fully understand this network of genes and role of PU.1 in myeloid cells and AD.
Restricted Content / Members Only

You cannot view this content because It is available to members only. Please or Register to view this area.