Neurology Central

Alzheimer’s tau structure revealed in first-of-its-kind study

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Researchers at the Medical Research Council Laboratory of Molecular Biology (MRC LMB; Cambridge, UK), have presented the atomic structures of the abnormal tau filaments that are associated with Alzheimer’s disease (AD). In the first study of its kind, findings show cryo-electron microscopy maps and associated atomic models of paired helical and straight filaments taken from the brain of a patient with AD.
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