Neurology Central

Alzheimer’s and sleep: an interview with Ram Sharma

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Ram Sharma is an Assistant Research Scientist at New York University (NY, USA), whose research into the relationship between Alzheimer’s pathology and sleep spindles was highlighted at the recent Alzheimer’s Association International Conference (AAIC; London, UK, 16–20 July 2017) as one to watch. We caught up with Ram to learn more about his research and his outlook for the field.

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Can you tell us about your background and current role(s)?

I was born and raised in the small town of Agra in India, home to one of the premiere institutes of leprosy research in Asia, which inspired me to pursue medical research. I received training from L.L.R.M Medical College (Uttar Pradesh, India), and served for 3 years as a resident of psychiatry in rural India. The burden of dementia in the community is often masked by more life threating diseases in developing countries. However, with the current growth rate and improvements in health care quality in developing countries, I believe the Alzheimer’s disease (AD) burden will be quite evident in the coming decades.  With little or almost no awareness about dementia in third world countries, there is an even higher chance that these countries will be worst affected by AD in the future. This purview motivated me to work in AD-related research.

Currently, I am working as an Assistant Research Scientist at New York University (NYU), focusing on the natural history of AD and its risk factors. In recent years there has been a spur in literature on sleep and its role in AD pathology. Exploring this possibility, we are looking for relationships between different stages of sleep, EEG characteristics and AD biomarkers.

Please can you tell us about the work that you were presenting at AAIC?

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