Authors: Jade Parker, Future Science Group
Studies presented at the Alzheimer’s Association International Conference (AAIC; 22–26 July, IL, USA) have highlighted sex differences associated with dementia and Alzheimer’s disease across the life course, including the first ever large-scale study of reproductive history and dementia risk in women.
Key studies include:
- Associations between dementia risk and number of children, number of miscarriages, age at first menstrual period, and reproductive period
- In a separate study, a correlation between cumulative months of pregnancy and Alzheimer’s risk
- A need for sex-based standards for cognitive assessments, to improve early detection in women
Link between reproductive history and dementia risk in women
The first-ever large-scale epidemiological investigation in the USA of various aspects of reproductive history and dementia risk has revealed a correlation between risk of dementia and the number of children, number of miscarriages, age at the time of first menstrual period, age at natural menopause and reproductive period.