Authors: Alice Bough, Future Science Group
Researchers from the Wellcome Sanger Institute (Cambridge, UK) and colleagues have performed a genome-wide association study to determine if common genetic variation has an impact on the risk of many rare genetic disorders.
The paper, which has been published in Nature, may help researchers better understand the neurodevelopmental disorders that thousands of children are born with every year.
The paper utilizes data collected during the Deciphering Developmental Disorders study in which DNA was collected from thousands of patients whose neurodevelopmental genetic disorders were considered to be monogenic. The genomes of 6987 children suffering from a range of disorders such as autism were compared with the genomes of healthy individuals.