Why are migraines more common in women? New sex-specific insights revealed

A team of researchers from the University of Texas at Dallas (TX, USA) have determined that CGRP exhibits pain effects in a sex-specific manner. The paper, published in the Journal of Neuroscience, may help us understand why women are more likely to experience migraines than men. For several decades CGRP has been known to play a prominent role in migraines. However, preclinical research into this role has often only involved male animals. “This leaves the question of neurobiological sex differences unanswered,” commented Greg Dussor (University of Texas at Dallas). It has also not yet been determined where in the body...