Neurology Central

Risk of dementia may be increased with certain anticholinergics, study suggests

Certain types of commonly prescribed drugs used to treat bladder conditions, Parkinson’s disease and depression could significantly increase the risk of dementia later in life, according to a recent study.

The research, which has been published in JAMA Internal Medicine, was carried out by researchers from the University of Nottingham (UK). The team identified that there was a nearly 50% increased risk of dementia among patients aged 55 and over who had used strong anticholinergic medication daily for 3 years or more.

Within the nested case-control study, the investigators examined the medical records of 58,769 patients with a diagnosis of dementia and 225,574 patients without a diagnosis of dementia. All participants were aged 55 and over and registered with UK general practitioners contributing data to the QResearch database (between 1 January 2004 and 31 January 2016).

Restricted Content / Members Only

You cannot view this content because It is available to members only. Please or Register to view this area.