Neurology Central

Exosomes: the key to treating and diagnosing neurodevelopmental disorders?

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A multidisciplinary team from Scripps Research (CA, USA) examined exosomes from a disease model of Rett syndrome and from healthy human neurons. Through several experiments, the research team found evidence suggesting exosomes could play an important role in brain circuits, cell signaling and communication.

The research is available to read in the Proceedings of the National Academy of Sciences.

“During different stages of brain development, signaling between cells is absolutely essential,” explained study author Hollis Cline (Scripps Research). “We found that exosomes are one of the ways cells communicate these signals.”

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