Neurology Central

Blood pressure changes in mid-30s linked to poorer brain health


A recent study led by researchers at University College London (UCL; UK) has indicated that changes in blood pressure in individuals as young as 36 could be linked to markers of poorer brain health.

The findings from the study, termed Insight 46, are published in The Lancet Neurology.

Insight 46 is a neuroscience sub-study of the Medical Research Council National Survey of Health and Development (NSHD), which is the longest running birth cohort in the UK. The study is designed to follow over 500 birth cohort members to determine early signs and risk factors for dementia as they reach their 70s.

Find out more about Insight 46 here:

Although blood pressure in midlife has been linked to a higher risk of dementia previously, the mechanism by which this happens, including the time when blood pressure is most important, remain uncertain.

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