Neurology Central

Patterns of brain activity could predict early Alzheimer’s symptoms in mice


Researchers at Gladstone Institutes (CA, USA) have been investigating the cerebral activity associated with Alzheimer’s disease. In a new study published in Cell Reports, they demonstrate that particular patterns of brain activity could indicate whether a young mouse will develop Alzheimer’s prior to any noticeable signs of memory loss.

In previous research, senior author of the study Yadong Huang (Gladstone Institutes) and his team investigated sharp-wave ripples (SWRs), which are brain patterns that play a direct role in spatial learning and memory formation. They occur when the brain of a mouse or human replays a recent memory of moving through a space.

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