A recently published study has indicated that eliminating microglia could significantly reduce tau-linked brain damage in mice, providing a path for novel treatments.
Browsing: Cognitive/neurodegenerative disorders
Researchers have discovered that more women and less men are diagnosed with amnestic mild cognitive impairment when sex-specific scores are used.
In a recent follow-up study, researchers discovered that when used as a dietary supplement, choline was able to reduce symptoms associated with Alzheimer’s disease in female mice.
What are the main challenges surrounding primary prevention trials for Alzheimer’s? Should researchers be exploring alternative avenues to amyloid-β in these trials? Take a look at our interview with Randall Bateman to find out more.
What are the challenges surrounding clinical trial design for genetic therapies in terms of neurodegenerative diseases? What technological advances could help bring these therapies to the clinic more quickly? Find out in our video interview with Sarah Tabrizi.
The Insight 46 study has indicated that changes in blood pressure in people as young as 36 may be linked to poorer brain health later in life.
Genetic therapies represent a remarkable avenue for potentially slowing and preventing neurodegenerative diseases. This includes a first-in-human, gene-silencing treatment for Alzheimer’s disease. Find out more on this from Catherine Mummery.
In order to slow the accumulation of white matter lesions, researchers reveal that it is more effective to intensively control a person’s blood pressure compared to the standard care of high blood pressure.
In this video, we spoke with Henrik Zetterberg to find out how challenges with replication, reproducibility and specificity could be addressed in the field.