Researchers have discovered that a gene-editing technique, which silences gene transmitting pain signals, is effective in mice that had been suffering from the painful effects of chemotherapy.
What are the challenges associated with identifying risk genes for Alzheimer’s disease? What more needs to be done to successfully translate this genetic data into potential therapeutics? Watch our video with Owen Peters to find out more.
A woman genetically predisposed to have early-onset autosomal dominant Alzheimer’s disease at the age of 40 did not display symptoms until her 70s. This has been linked to the presence of a rare gene variant termed APOE3ch.
What are the challenges surrounding clinical trial design for genetic therapies in terms of neurodegenerative diseases? What technological advances could help bring these therapies to the clinic more quickly? Find out in our video interview with Sarah Tabrizi.
Left-handed people have been reported to have certain genetic regions that are associated with brain architecture in areas involved with language.
Genetic therapies represent a remarkable avenue for potentially slowing and preventing neurodegenerative diseases. This includes a first-in-human, gene-silencing treatment for Alzheimer’s disease. Find out more on this from Catherine Mummery.
In this editorial, we shed light on the key advances made in migraine genetics, their neurobiology and what the future might hold for the field.
In a recent study, researchers have discovered a possible link between high LDL cholesterol and early-onset Alzheimer’s disease.
For the first time, researchers have revealed that autism could result from mutations in the noncoding regions of the human genome.