0 SfN18: The potential of gene therapy in neurological disorders
Gene therapy for disorders such as amyotrophic lateral sclerosis, Parkinson’s disease and Batten disease has seen success in animal models.
Browsing: Genetics
0 Treasure trove of 102 genes associated with autism identified
In the largest exome sequencing of autism spectrum disorder to date, researchers have identified 102 possible gene candidates.
0 Monogenic neurodevelopmental disorders may not be as simple as they seem
Scientists at The Wellcome Sanger Institute have determined that the risk of suffering from a range of monogenic neurodevelopmental genetic disorders can be affected by common genetic variations.
0 From risk to resilience: understanding the role of genetics in Alzheimer’s disease
At AAIC 2018, we had the pleasure of speaking with Catherine Kaczorowski about the innovative work she is doing to accelerate drug discovery in Alzheimer’s disease.
0 Build-up of RNA-binding proteins found in individuals with ALS and dementia
Researchers have revealed that RNA-binding proteins accumulate in the brains of people with non-heritable amyotrophic lateral sclerosis and frontotemporal dementia.
0 Personalized neurological fingerprint could increase effectiveness of Alzheimer’s treatment
Researchers have developed a personalized neurological footprint, which uses a link between brain physiology, genetic profile and response to therapeutics, to predict the effectiveness of aiming treatment at various targets within individual patients.
0 FENS 2018: Stem cells and brain organoids – the ‘hot spots’ of brain research
Stem cells and brain organoids were the focus of a symposium during the FENS Forum of Neuroscience (7–11 July, Berlin,…
0 FENS 2018: Genetic variations in psychiatric disorders may affect response to treatment
Scientists have demonstrated how variations in a gene linked to anxiety and depression could affect a patient’s response to treatment.
0 FENS 2018: Epigenetics – trans-generational effects of traumatic experiences
Research has demonstrated that traumatic effects caused by a stressful experience can lead to epigenetic changes to gene activity; these changes can be passed on, and therefore result in behavioral changes in future generations.
0 Could psychiatric disorders share an underlying genetic basis?
In an international collaboration, researchers have determined that psychiatric disorders may have important molecular similarities that are not reflected in current diagnostic categories.
