This Editorial article provides an insight into how pharmacogenomics can assist in guided dosing of fentanyl for the treatment of pain.
Researchers have developed computer models to further understanding the behavior of protein fragments and fibril aggregation in Huntington’s disease development.
James Coffman responds to questions from our recent webinar, ‘How chronic stress experienced during early development epigenetically programs adult disease risk’.
In new research, the first live-attenuated Zika vaccine has been demonstrated to protected mice against the virus after a single dose.
A large, multicenter, genome-wide association study has identified a number of new genetic risk loci for malignant brain tumors.
Researchers use epigenome-editing technology to repress cytokine cell receptors, preventing tissue degeneration and pain.
Dr Coffman is currently studying the mechanisms by which chronic early-life stress increases adult disease risk, using zebrafish as a model organism to ask how such stress affects immune system development and regulation.
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Epidemiological studies have shown that chronic stress experienced very early in life—even prenatally—increases the risk of developing inflammatory disease in adulthood, including mental health disorders such as anxiety and depression.
Study also reveals differences in the metabolism of macular telangiectasia sufferers that could lead to onset of the disease.
In this interview, Drs Silverman and Buscher discuss their work, and how these two rare diseases are shedding light not only on each other, but also a wealth of other neurological disorders.