0 NCTalks at AAIC 2017: Julie Williams on Alzheimer’s genetics
While at AAIC 2017 in London, Lauren Pulling (Editor, NC) spoke to Julie Williams about her extensive work in Alzheimer’s genetics and risk factors.
Browsing: Genetics
0 DNA methylation and transcription onset in the brain
The goal of this study was to test the state of methylation of transcription start positions in DNA that are actively involved in transcription.
0 Small-molecule BDNF mimetic may improve symptoms of Rett syndrome
Researchers at the University of Alabama at Birmingham (Birmingham, AL, USA) have demonstrated that a small-molecule BDNF mimetic, previously shown to aid respiratory problems in Rett Syndrome, also improves spatial memory and motor function.
0 Neurotransmitter receptor genotypes associated with mental and behavioral disorders
This study generates a novel dataset of associations for disorders such as major depression and schizophrenia, providing a global perspective for their genetic etiology.
0 Alzheimer’s disease risk linked to gene network expressed in myeloid cells
Researchers have identified a network of genes expressed by myeloid cells that are linked to late-onset Alzheimer’s disease (AD).
0 Genetic variations may predispose children to develop high-risk neuroblastoma
Investigators hope that their findings will assist in the development of targeted treatments for pediatric brain cancers.
0 Huntington’s pathology alleviated by CRISPR/Cas9 gene editing
An international research team have shown that gene editing reverses Huntington’s symptoms without off-target effects in a mouse model.
0 Brain stimulation in Huntington’s disease
This article summarizes the results of brain stimulation in HD and gives a perspective on the therapeutic role for neuromodulatory brain stimulation methods.
0 Huntington’s disease blood biomarker identified
UCL (London, UK) researchers have demonstrated that levels of neurofilament protein in the blood are raised in Huntington’s patients and carriers of the disease.
0 Controversial Alzheimer’s disease risk gene explained in new study
Research suggests that family history explains conflicting study results for Alzheimer’s disease risk gene TOMM40.