Karmakar & Reilly review what is known about the role of NF1 mutation in immune cell function & the role of immune cells in promoting tumorigenesis in NF1.
Browsing: CNS Oncology
In this article, the authors report the case of a patient suffering from a melanoma with multiple brain metastasis, treated with BRAF and MEK double blockade, with impressive and rapid response.
This summary guideline outlines methods for starting patients on TTFields, for monitoring patient response to therapy and provides a framework for evaluating when therapy should be re-planned.
This review discusses targeted therapies for glioblastoma and different attempts to identify biomarkers of response to drugs.
Glioblastoma provides a good opportunity for evaluation of immunotherapy as a targeted treatment for patients.
This review explores the role of the transcription factor, termed SOX2, in brain tumors, focusing specifically on studies of glioblastoma and medulloblastoma.
Better prognosis for glioblastoma patients with seizures has raised questions about the anti-tumor properties of antiepileptic drugs. This article reviews the potential mechanisms associated with this.
This article compares the clinical utility of Graded Prognostic Assessment and Recursive Partitioning Analysis in prognosis prediction for patients with brain metastases.