The mechanisms underlying chronic pain conditions are currently poorly understood. This article considers recent advancements in omics technologies and how this may impact our understanding of the biological pathways involved with chronic pain and ultimately development of effective biomarkers and therapies.
Browsing: Pain Management
The ‘opioid epidemic’ has sparked discussion over the use of opioids in the treatment of chronic noncancer pain, but is this something limited to North America or is this occurring across the world?
G Lorimer Moseley et al. review the impact of group composition in cognitive-behavioral therapy for chronic pain and present a conceptual framework for analyzing group-composition within the context of pain management.
This article explores the mechanisms of deep pain and the role deep pain can play in other chronic pain syndromes.
Understanding systems associated with cognitive or emotional processing may help to explain the psychology underlying pain perception. This article reviews these pain modulatory systems in an effort to guide development of novel pain therapeutics.
Microglia have increasingly been implicated in the pathogenesis of neuropathic pain, this article explores the relationship and the transcriptional factors driving the association.
Pain Management Commissioning Editor, Nick Ward, talks to diabetes expert Solomon Tesfaye (University of Sheffield) about his career and hopes for PL37, a novel dual enkephalinase inhibitor currently being trialled for treatment of diabetic neuropathy.
This article reviews pain management processes in a correctional setting and key research which could influence these interventions.
This short commentary explores the role of parent management in reducing the pain associated with child vaccinations.
This article discusses a major sodium ion channel termed Nav1.7 that has been identified in humans as essential for pain detection, considering strategies for targeting the channel as a potential alternative to opiates and other short acting pain killers with often significant adverse effects.