Biomarkers are commonly used in clinical, research and industry settings to evaluate the safety and/or effectiveness of drugs. They can also track disease progression over time and serve as surrogate endpoints in clinical trials. Additionally, biomarkers can lead to significant cost reductions during drug development by enabling early proof-of-concept studies for novel therapeutic targets, thus reducing costly drug attrition rates.
With such a broad therapeutic scope in neurological diseases, plus significant leaps being made rapidly in biotechnology, biomarker discovery and development is set to be an area of continuing major growth in coming years. Thus, we wanted to delve deeper into this exciting field, exploring clinical uses, challenges and future directions through a range of news pieces, interviews, journal articles and expert opinions.