CNS/PNS/SNS: All Phases trials

Early Stage Amyotrophic Lateral Sclerosis Phrenic Stimulation (RespiStimALS)

Phenique nerve stimulation NeurX™

Phase III

France

Recruiting

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Phase IIb Study of Intranasal Glutathione in Parkinson's Disease ((in)GSH)

Reduced Glutathione

Phase II

United States

Recruiting

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Efficacy of Isradipine in Early Parkinson Disease

Isradipine

Phase III

United States, Canada

Recruiting

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Randomised Crossover Trial of Deep Brain Stimulation of Differential Posterior Subthalamic Area Regions in Parkinson's Disease and Tremor

Up to 3 mA, 60 us, 130 Hz deep brain stimulation, Empirical unblinded deep brain stimulation programming

Phase II

Australia

Recruiting

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Efficacy of L-threo DOPS on Orthostatic Hypotension Symptoms and Other Non-motor Symptoms in Patients With MSA (DOPS-AMS)

L-Threo DOPS

Phase II

France

Recruiting

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Treatment of Parkinson Disease and Multiple System Atrophy Using Intranasal Insulin

Intranasal Insulin

Phase II

United States

Recruiting

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Phase 3 Study of Dexpramipexole in ALS (EMPOWER)

Dexpramipexole

Phase III

Multiple worldwide locations

Completed

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Intramuscular Infusion of Autologous Bone Marrow Stem Cells in Patients With Amyotrophic Lateral Sclerosis (TCIM/ELA)

MNC (Mononuclear cells)

Phase I

Spain

Recruiting

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Ibudilast (MN-166) in Subjects With Amyotrophic Lateral Sclerosis (ALS) (IBU-ALS-1201)

Ibudilast (MN-166)

Phase II

United States

Recruiting

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Cell Therapy for Motor Neuron Disease/Amyotrophic Lateral Sclerosis

Stem Cell

Phase I

India

Recruiting

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Long-Term Extension Study in Participants With Multiple Sclerosis Who Have Completed Study 205MS301 (NCT01064401) to Evaluate the Safety and Efficacy of BIIB019 (EXTEND)

BIIB019 (Daclizumab High Yield Process)

Phase III

Multiple worldwide locations

Recruiting participants by invitation only.

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Investigating Mechanism of Action of DAC HYP in the Treatment of High-Inflammatory Multiple Sclerosis (MS)

DAC-HYP

Phase I

United States

Recruiting

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A Phase 2b/3 Study to Compare Efficacy and Safety of Masitinib to Placebo in the Treatment of Patients With Primary Progressive or Relapse-free Secondary Progressive Multiple Sclerosis

Masitinib

Phase II

Spain

Recruiting

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Endpoint Calibration for a Phase 2 Study of Lisinopril in Multiple Sclerosis

Lisinopril

Phase II

United States

Recruiting

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