CNS/PNS/SNS drug pipelines

Abbvie

ABBV-8E12

Progressive supranuclear palsy

Phase I


Sanofi

patisiran

Familial amyloidotic polyneuropathy

siRNA inhibitor targeting TTR

Phase III


Roche

Olesoxime

spinal muscular atrophy

Phase II


Shire

SHP-622

Friedreich's Ataxia

Phase I


Sumitomo Dainippon Pharma

AS-3201(ranirestat)

Diabetic neuropathy

Phase III


Teva Pharmaceutical Industries Ltd

Laquinimod

Multiple Sclerosis (Progressive forms), Huntington Disease

Immunomodulator

Phase II


Lilly

LY2216684 (edivoxetine)

Multiple CNS disorders

Phase II


Roche

RG1594 ocrelizumab

Primary progressive multiple sclerosis

Monoclonal antibody

Phase III