Parkinson’s progression could be slowed down by drug that treats enlarged prostate

Written by Kimberley Ndungu (Future Science Group)

A collaboration between researchers in China and The University of Iowa (IA, USA) resulted in combining basic molecular biology with big data to investigate the effects of terazosin – a drug typically used to treat enlarged prostate or prostatic hyperplasia – on the progression of Parkinson’s disease (PD). This study, published in the Journal of Clinical Investigation, followed co-senior author Lei Liu’s (Capital Medical University, Beijing, China) discovery that terazosin can block cell death. This cell-protective activity was reported to be due to the fact terazosin can activate the PGK1 enzyme, which is essential for cellular energy production. As reduced...

To view this content, please register now for access

It's completely free