Evaluation of over 10 million insurance claims in the USA provides evidence of “adverse selection” in the prescription of opioids.
Childhood abuse, promoter methylation of leukocyte NR3C1 and the potential modifying effect of emotional support
In the study, the authors assess the impact of child abuse victimization on methylation of a novel CpG site located in a CpG island shore within the NR3C1 promoter and further assess the potential buffering effect of having received emotional support in childhood.
Webinar Q&A follow-up: Manipulation of Abuse Deterrent Formulations at the Clinical Pharmacology Unit
Read the Q&A transcript and responses to the unanswered questions from our webinar on ‘Manipulation of Abuse Deterrent Formulations at the Clinical Pharmacology Unit’.
What is the opioid epidemic? What has caused it? How can we fix it? Pain expert Michael Schatman discusses.