A common mutation in a key enzyme involved in alcohol metabolism may increase damage in cells obtained from individuals with Alzheimer’s disease and in mice.
Findings from a new study – the largest of its kind – indicate that heavy alcohol consumption is the most significant risk factor for the development of dementia.
Researchers from Queensland University of Technology have identified a drug that could reverse the damaging effects of heavy alcohol consumption on neurogenesis.
A new study on mice has demonstrated that lithium chloride can impede the detrimental effects of fetal alcohol syndrome on the developing brain.
Promising pharmacogenetic targets for treating alcohol use disorder: evidence from preclinical models
This review explores promising novel genetic variants derived from preclinical models of alcohol consumption and dependence, and identifies novel pharmacogenetic targets that facilitate therapeutic intervention for the treatment of alcohol use disorder.
Andie Asimes discusses her work on binge alcohol consumption in adolescence and how the epigenetic consequences of this can lead to a higher predisposition for mental health disorders in offspring.
Take a look at our infographic – we explore our current knowledge of the interactions between alcohol and epigenetic mechanisms, and take a look at the latest research and drug targets.