This week in industry we’re taking a look at the discontinuation of umibecestat and Acthar® Gel for Alzheimer’s and ALS, respectively, as well as the drug discovery shift from the amyloid approach in the Alzheimer’s field.
Browsing: amyloid beta
Researchers have found that the sleep history and pattern of older men and women may predict the accumulation of proteins associated with Alzheimer’s disease.
In this review article from Biomarkers in Medicine, researchers explore the current application of blood-based markers to assess amyloid-β pathology.
A recent study has implicated that sticky proteins associated with neurodegenerative diseases could be transferred in mouse models.
Researchers have demonstrated that a DNA vaccine tested in mice is effective at reducing accumulation of tau and beta-amyloid proteins associated with Alzheimer’s disease.
Scientists have discovered a vicious feedback loop underlying brain degeneration in Alzheimer’s, which may explain why many drug trials have failed.
Researchers have suggested that anti-amyloid therapies would be most effective before individuals reach the threshold for preclinical Alzheimer’s disease.
A recent study suggests that beta-amyloid may be transmissable during surgery, but how strong is the evidence?
Researchers have observed improvements in the cognitive function of mice after reversing the formation of beta-amyloid plaques.
A collaborative study from researchers in Poland and Sweden has presented a novel combination of mechanisms that may lead to neuronal cell death in Alzheimer’s disease.