Manipulating the immune system to fight Alzheimer’s
A new study has highlighted the importance of immune system research in fighting Alzheimer’s disease.
Browsing: amyloid beta
Aggregation propensity of neuronal receptors: potential implications in neurodegenerative disorders
The propensity of a protein to form amyloid assemblies is imprinted in its sequence and can be read using computational approaches. This article utilizes four different algorithms to analyze the presence of aggregation-prone regions in the sequence and structure of neuroreceptors.
Treating neurodegenerative disease with tyrosine kinase inhibitors
Charbel Moussa discusses his exciting work into the use of FDA approved tyrosine kinase inhibitors to clear toxic neuronal proteins via autophagy.
Review of ‘the potential role of arterial stiffness in the pathogenesis of Alzheimer’s disease’
This review discusses the evidence linking arterial stiffness, hypertension and brain structural abnormalities in older adults.
New technique reveals potential amyloid beta structure
A modified version of Raman Spectroscopy has revealed an unexpected structure of amyloid beta.
Is there a link between the sleep–wake cycle and Alzheimer’s pathology?
Many previous findings suggest that understanding the causal relationship between the sleep–wake cycle and Alzheimer’s disease pathologies will provide novel insight into the pathophysiology of Alzheimer’s. This article explores the hypotheses.
ßCTF implicated in the earliest stages of Alzheimer’s disease
An early precursor of the amyloid beta peptide, ßCTF, has been found to initiate a number of processes that can lead to the loss of neurons critical for memory formation in early Alzheimer’s disease.
