Researchers have developed a 3D, all-human, in vitro model to help overcome challenges in delivering drugs to the brain.
Browsing: blood-brain barrier
NIH researchers look to a zebrafish model to improve our understanding of the blood–brain barrier’s neuroprotective cells.
In the quest to cross the BBB, researchers have developed immunoliposomes targeted to BBB receptors and α-synuclein that could potentially enable the transport of drugs to reach one of the drug targets in Parkinson’s disease.
Study investigates the connectivity of neurons from three areas of the brain that are closely associated with schizophrenia.
A novel drug delivery system will be used in upcoming Phase I-II clinical trials of drug candidate CDNF for the treatment of Parkinson’s disease.
This article reviews the potential role of neuroinflammation as a promoter of oncogenesis within the brain, focusing in on traumatic events such as traumatic brain injuries.
A new soluble form of aspirin has shown efficacy against glioblastoma in laboratory tests.
Novel imaging technique may help predict stroke patients that will benefit from endovascular therapy
A new study from the National Institute of Health, National Institute of Neurological Disorders and Stroke (MD, USA) has indicated a potential link between the extent of damage to the blood-brain barrier following stroke and the severity of bleeding following invasive stroke therapy.
This review will discuss the role of the complement system in brain degenerative pathology.
Getting therapies through the blood-brain barrier is one of the biggest hurdles for Alzheimer’s and Parkinson’s treatments. This article discusses the use of nanometric drug delivery systems in Alzheimer’s and Parkinson’s disease.