In his latest column, David Howett reviews a recent paper from Gunn-Moore et al. on the relationship between Alzheimer’s disease and Type 2 diabetes.
Browsing: disease models
Japanese researchers have successfully implanted human induced pluripotent stem cell-derived dopaminergic neurons into primate Parkinson’s models.
Environmental change, and a growing and more connected population will promote vector-borne disease risk further. In this opinion piece, the authors discuss the role of climate modeling in disease prediction and epidemiology.
Studies in aged chimpanzees have identified neuropathological hallmarks similar to those observed in the human Alzheimer’s diseased brain.
The enzyme asparagine endopeptidase could be a key mediator in the cleavage and aggregation of alpha-synuclein in Parkinson’s disease.
Research presented at ASM Microbe has reported a Zika vaccine based on the NS1 protein can induce protective immunity in mouse models after a single dose.
This review explores commonly used experimental models of GBM, recent improvements to these models and strategies for developing advanced models.
Researchers have developed computer models to further understanding the behavior of protein fragments and fibril aggregation in Huntington’s disease development.
Mark Stewart shares his group’s work on developing an appropriate small animal model for SUDEP, a condition that presents a significant challenge to researchers, particularly given that it occurs rarely and under circumstances where physiological data are seldom available
Angelman syndrome and Dup15q syndrome: two rare diseases working together to solve each other’s puzzles – a conversation with Jill Silverman and Nathalie Buscher
In this interview, Drs Silverman and Buscher discuss their work, and how these two rare diseases are shedding light not only on each other, but also a wealth of other neurological disorders.