Serotonin receptor agonist discovered in a zebrafish model decreased seizure frequency in small pediatric clinical trial.
Browsing: disease models
Christian Naus discusses his work on 3D glioma models, which could facilitate personalized medicine approaches to one of the brain’s most significant threats.
Researchers have successfully reduced tau deposits and prevented neuronal death with novel drug in both mouse and primate models.
Newly identified molecular mechanisms underlying multiple sclerosis could lead to alternative drug treatments
Inhibiting the CXCR2 and LTBR receptors may be an effective treatment strategy for multiple sclerosis patients who are unresponsive to interferon-beta treatment.
Study builds upon current knowledge on Zika virus and its effects on the brains of newborns, in a step that could one day help to eliminate the birth defects caused by this disease.
Utilizing mathematical modeling, researchers have identified specific brain atrophy patterns that appear to be linked to the loss of particular cognitive abilities in Alzheimer’s disease.
Research on the manifestation of CNS diseases in the retina highlights a promising route for non-invasive screening.
We speak to Marc Goodfellow (University of Exeter, UK), who, along with his colleagues, is developing new techniques to identify specific brain regions that trigger seizures in epilepsy.
Scientists utilize a novel co-culture method to identify a potential target for new treatments against Huntington’s disease.
We recently featured the review ‘Utilization of stem cells to model Parkinson’s disease – current state and future challenges’ – here, the article’s co- author, Jens Schwamborn, gives us some background on his research.