Researchers may be able to diagnose and treat Alzheimer’s disease before it becomes symptomatic, through a dietary drug which could be more effective than current treatments.
Research has demonstrated that traumatic effects caused by a stressful experience can lead to epigenetic changes to gene activity; these changes can be passed on, and therefore result in behavioral changes in future generations.
A collection of the biggest news to come out of the Society for Neuroscience’s annual meeting, Neuroscience 2017, as well as interviews with the researchers behind the science.
A series of research presented at SfN’s Neuroscience 2017 has shed more light on the mechanism by which stress negatively impacts the brain, potentially highlighting future therapeutics.
The goal of this study was to test the state of methylation of transcription start positions in DNA that are actively involved in transcription.
In this perspective article, the authors draw attention toward the pharmacoepigenomic influence of antipsychotic drugs, and distinguish its significance from therapeutic response and schizophrenia pathogenesis.
Webinar Q&A follow-up: How chronic stress experienced during early development epigenetically programs adult disease risk
James Coffman responds to questions from our recent webinar, ‘How chronic stress experienced during early development epigenetically programs adult disease risk’.
Researchers use epigenome-editing technology to repress cytokine cell receptors, preventing tissue degeneration and pain.
Dr Coffman is currently studying the mechanisms by which chronic early-life stress increases adult disease risk, using zebrafish as a model organism to ask how such stress affects immune system development and regulation.
Andie Asimes discusses her work on binge alcohol consumption in adolescence and how the epigenetic consequences of this can lead to a higher predisposition for mental health disorders in offspring.