Take a look at our infographic – we explore our current knowledge of the interactions between alcohol and epigenetic mechanisms, and take a look at the latest research and drug targets.
A review of biological pathways and mechanisms underlying the social gradient in health, with particular emphasis on behavioral stress influences.
The authors review how dysregulation of histone methylation has emerged as a major driver of neurodevelopmental disorders such as intellectual disabilities and autism spectrum disorders.
Childhood abuse, promoter methylation of leukocyte NR3C1 and the potential modifying effect of emotional support
In the study, the authors assess the impact of child abuse victimization on methylation of a novel CpG site located in a CpG island shore within the NR3C1 promoter and further assess the potential buffering effect of having received emotional support in childhood.
Biological underpinnings of trauma and post-traumatic stress disorder: focusing on genetics and epigenetics
The authors highlight some of the key genetic risk factors identified for PTSD, and the evidence that epigenetic processes might play a role in the biological response to trauma, as well as being potential biomarkers of PTSD risk. We also discuss important considerations for future research in this area.
Can we identify meaningful epigenetic effects on human brain function and related risk for mental illness?
The authors briefly consider the challenges of linking environmental risk to mechanisms of psychopathology and possible therapeutic targets and discuss the potential avenues for moving forward through the lens of their ongoing work.
Reid Alisch discusses the role of epigenetics in neuropsychiatric disorders, and how new epigenetic research could change future research and treatment practices.
In this interview conducted by our colleagues at EpigenomicsNet, we discuss epigenetic links between folate supplementation and fetal neurodevelopment, providing us an insight into the ongoing EpiFASSTT study.
This Epigenomics article examines genetic influences on mental health, focusing on the recent identification of links between 5hmC and mental illness and it’s clinical relevance.
This article provides an overview of the major events in human fetal brain development and reviews the classes of genes targeted by methylation and linked to neurological and behavioral development.