Long-term antibiotic treatment may reduce the size of amyloid plaques and could alter the appearance of microglia in the brains of male mice.
Whilst at the ARUK Conference 2019, we had the pleasure of speaking with Hugh Perry about neuroinflammation and Alzheimer’s disease, particularly the role of microglia in brain homeostasis.
In this interview, we spoke with Justin Lathia about sexual dimorphism in glioblastoma, including his talk on sex differences in microglia and the glioma microenvironment.
Excessive stress during childhood or fetal development can have long-term consequences on the brain, with research from SfN Neuroscience uncovering new mechanisms and therapeutic targets.
Recent research has reported on the sex-specific differences in microglia, indicating that this could change how we treat neurological diseases.
A new study has demonstrated a distinctive pattern of unusual gene activity in the brains of autistic individuals; a finding that indicates several possible new drug targets.
Researchers have identified that microglia proliferation could have a role in neuropathic pain, indicating a new avenue for research into novel treatments.
New research indicates that phagocytosis mediated by microglia is disrupted in neurodegenerative diseases, following observations in brain tissue taken from epilepsy patients.
Neural circuitry changes in the brain induced by chronic cocaine use can be reduced through microglial release of TNF-α, providing hope for the development of addiction-suppressing therapies.