In this study the authors investigate the efficacy of bone marrow-derived mesenchymal stem cells in combination with solid lipid nanoparticles in a rat model of Alzheimer’s disease
Tetronic® 904-containing polymeric micelles overcome the overexpression of ABCG2 in the blood–brain barrier of rats and boost the penetration of the antiretroviral efavirenz into the CNS
This article from Nanomedicine assesses the involvement of ABCG2 in the pharmacokinetics of efavirenz in the blood–brain barrier and investigates a novel nanotechnology strategy to overcome its overexpression under a model of chronic oral administration.
This editorial discusses the emergence of a new tehcnique that may enable neuropharmacologists and others to overcome the challenge of developing drug molecules capable of permeating the blood-brain barrier.
A modified version of Raman Spectroscopy has revealed an unexpected structure of amyloid beta.