To explore the intricacies of the manipulation of abuse deterrent formulations (ADFs) in the clinical pharmacology unit (CPU) and its relationship to in vitro studies.
The opioid epidemic and the long-term opioid therapy for chronic noncancer pain revisited: a transatlantic perspective
The ‘opioid epidemic’ has sparked discussion over the use of opioids in the treatment of chronic noncancer pain, but is this something limited to North America or is this occurring across the world?
New research demonstrates that electrical stimulation of deep midbrain structures blocks pain signals in the spinal cord of rats, indicating a possible new direction for the treatment of chronic pain.
Naltrexone could improve relapse rates for heroin addicts and provide an alternative to currently controversial treatments.
This article discusses a major sodium ion channel termed Nav1.7 that has been identified in humans as essential for pain detection, considering strategies for targeting the channel as a potential alternative to opiates and other short acting pain killers with often significant adverse effects.