Using fluorescent tags, a team of researchers discovered a novel mechanism for synaptic plasticity that may have pharmacological applications in the treatment of epilepsy.
High-grade gliomas may be able to wire themselves into the healthy brain, receiving and interpreting electrical signals from normal neurons.
Researchers have uncovered the role of calcium and how it interacts with alpha-synuclein in the development of Parkinson’s disease.
Research suggests increasing synaptic activity could alleviate SMA symptoms: motor function of mice was improved when treated with a glutamate receptor stimulant.
Reducing mouse model brain levels of the protein Ephexin5 prevented the loss of excitatory synapses that typically leads to memory loss in Alzheimer’s disease.
Recent findings have indicated that bumetanide could be used to block the formation of aberrant neural connections in the brain that form after a convulsive epileptic seizure.
A new mechanism that controls nerve cell communication has been identified, which could be a major advance in understanding neurodegenerative disorders.
A group at Yale University (CT, USA) have developed a new method for quantifying synaptic density within the human brain.
Genetic analysis reveals gene variants linked to synaptic pruning within schizophrenia patients.
New research has uncovered a new molecular mechanism characterizing synapse loss in Alzheimer’s disease.