This article discusses two potential neural networks, the serotonergic system and the OTergic system, that could prove to be particularly useful targets for endocrine therapy.
Browsing: targeted therapy
The enzyme asparagine endopeptidase could be a key mediator in the cleavage and aggregation of alpha-synuclein in Parkinson’s disease.
Researchers have identified a network of genes expressed by myeloid cells that are linked to late-onset Alzheimer’s disease (AD).
This review provides a comprehensive overview of miRNAs as biomarkers and therapeutic targets for neurodegenerative disorders.
Identification of Apo B48 and other novel biomarkers in amyotrophic lateral sclerosis patient fibroblasts
This study utilized SILAC proteomic analysis of human ALS patient and population control fibroblasts to discover proteins that are differentially regulated in ALS and may serve as useful biomarkers.
This study investigated the influence of HLA class-I and -II genes in the response to IFN-β in relapsing-remitting multiple sclerosis (MS) patients.
Researchers identify a distinct group of hypothalamic neurons implicated in anxiety that could be targeted in future treatments.
Researchers at the University of Cambridge (UK) have uncovered new information about the mechanism underlying the build up of amyloid plaques within the brains of Alzheimer’s disease patients.
This article reviews the potential role of neuroinflammation as a promoter of oncogenesis within the brain, focusing in on traumatic events such as traumatic brain injuries.
Hcn1, a gene that regulates neuronal excitability, has been identified in mice as a potential target for the treatment of trauma- and stress-related disorders, and may explain symptom and treatment response variability.