A recent study has implicated that sticky proteins associated with neurodegenerative diseases could be transferred in mouse models.
Researchers have suggested that anti-amyloid therapies would be most effective before individuals reach the threshold for preclinical Alzheimer’s disease.
Rebecca Gabriele (KCL) reports on Day 2 of the ARUK Conference, including metabolism, neurodegeneration, tau, and insights into dementias from other diseases.
For the first time, researchers have been able to examine the exact link between amyloid- β and tau in an animal model of the Alzheimer’s brain, providing hope for new therapeutic targets.
A novel study into TREM2 has demonstrated that the gene can pose both risks and benefits to Alzheimer’s patients.
In this interview, Grace discusses her research, exciting new avenues for dementia research, and some of the challenges faced by early career researchers.
Studies in aged chimpanzees have identified neuropathological hallmarks similar to those observed in the human Alzheimer’s diseased brain.
Researchers have presented cryo-electron microscopy maps and atomic models of paired helical and straight filaments taken from the brain of an Alzheimer’s patient.
In this interview, Prof Wischik discusses his 30 years’ experience in the field, the latest developments at TauRx, and what we can expect from tau research the next 10 years.
Journal Watch: Lost in propagation – tau induces neuron loss and grid cell dysfunction in transgenic mice
Researchers at Colombia University, New York (NY, USA), have recently demonstrated that tau pathology induces dysfunction in cells specifically tuned to compute spatial information.