Researchers have found that the sleep history and pattern of older men and women may predict the accumulation of proteins associated with Alzheimer’s disease.
In a study focused on a group of former professional athletes who have experienced multiple concussions, over half the group were reported to have higher levels of tau protein biomarkers in their cerebrospinal fluid.
An experimental PET scan was used to detect elevated levels of abnormal tau protein in regions of the brain affected by CTE in living former NFL players.
The Medical Research Council (MRC; London, UK) has determined the atomic structures of abnormal tau filaments related to chronic traumatic encephalopathy (CTE) and discovered that the structure is different to tau filaments seen in Alzheimer’s disease.
A recent study has revealed that people who experience sleep apnea also present with higher levels of tau in the entorhinal cortex.
In this research article from Biomarkers in Medicine, researchers determine if serum levels of tau and BDNF can be used as severity biomarkers in multiple sclerosis.
A recent study has implicated that sticky proteins associated with neurodegenerative diseases could be transferred in mouse models.
Researchers have suggested that anti-amyloid therapies would be most effective before individuals reach the threshold for preclinical Alzheimer’s disease.
Rebecca Gabriele (KCL) reports on Day 2 of the ARUK Conference, including metabolism, neurodegeneration, tau, and insights into dementias from other diseases.
For the first time, researchers have been able to examine the exact link between amyloid- β and tau in an animal model of the Alzheimer’s brain, providing hope for new therapeutic targets.