Researchers have synthesized an artificial human prion for the first time, in an attempt to understand their structure, manner of replication and infectivity.
Browsing: toxic proteins
The interaction of prion protein and hemin, a therapeutic opportunity for Creutzfeldt-Jakob disease and cerebral hemorrhage?
Novel research has indicated that the interaction between cellular prion protein and hemin may upregulate hemoglobin synthesis; findings that have potential therapeutic implications for both Creutzfeldt-Jakob disease and cerebral hemorrhage.
Peptide toxins derived from the venom of the Peruvian green velvet tarantula, Thrixopelma pruriens, could serve as inhibitors of an important pain receptor in the brain.
New research has uncovered a new molecular mechanism characterizing synapse loss in Alzheimer’s disease.
The propensity of a protein to form amyloid assemblies is imprinted in its sequence and can be read using computational approaches. This article utilizes four different algorithms to analyze the presence of aggregation-prone regions in the sequence and structure of neuroreceptors.