For our Spotlight on biomarker discovery and development we carried out a survey to gain insights into biomarkers used, their challenges and future outlook.
Research has demonstrated that traumatic effects caused by a stressful experience can lead to epigenetic changes to gene activity; these changes can be passed on, and therefore result in behavioral changes in future generations.
Michael discusses his work, progress towards diagnosis of chronic traumatic encephalopathy in life and his thoughts on the latest in CTE research.
In this session at the American Academy of Neurology Annual Meeting, eight abstracts on TBI were presented with discussion particularly focusing on sports injury, some of which we highlight below.
In celebration of International Women’s Day, we spoke to Twyila about her accomplished career, gender challenges in nursing, and finding that elusive work–life balance.
Researchers have uncovered a role for the gene FKBP5 in memory formation following traumatic events, and suggest that manipulation of the gene could help prevent PTSD.
Biological underpinnings of trauma and post-traumatic stress disorder: focusing on genetics and epigenetics
The authors highlight some of the key genetic risk factors identified for PTSD, and the evidence that epigenetic processes might play a role in the biological response to trauma, as well as being potential biomarkers of PTSD risk. We also discuss important considerations for future research in this area.
A round-up of this year’s Social Issues Round Table, which aimed to encourage discussion and debate on the controversial and growing field of concussion, with a particular focus on sports and military settings.
Results from a recent clinical trial indicate that a low dose of the drug could act as a suitable means of reducing the risk of depression following traumatic brain injury.
Hcn1, a gene that regulates neuronal excitability, has been identified in mice as a potential target for the treatment of trauma- and stress-related disorders, and may explain symptom and treatment response variability.