3D stem cell cultures show promise for improving the treatment of neurodegenerative diseases

Written by Alice Bough, Future Science Group

Credit: Tufts University

Researchers from Tufts University (MA, USA) and the Jackson Laboratory (CT, USA) have collaborated to develop 3D in vitro human tissue culture models for the CNS.  The tissue culture models were created using cell lines from healthy individuals and from people with Parkinson’s disease and Alzheimer’s disease. The paper, which has been published in ACS Biomaterials Science and Engineering, may help researchers better understand the progression of neurodevelopmental diseases and allow for the exploration of new treatment options. The study expands upon previous work in which similar 3D models were grown utilizing stem cells from rodents. Human induced pluripotent stem...

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