Lauren Pulling, Editor, explores the longest-running lifetime cohort study in the world, including the new neuroscience clinical sub-study, Insight 46.
Recent research led by Vemuri et al. indicates that a variety of risk factors influencing amyloid deposition are distinct from Alzheimer’s disease-pattern neurodegeneration.
A call for investigating early-life origins of cognitive reserve in low- and middle-income countries utilizing routinely collected and cohort data approaches.
In this edition of our new column, #NCintroduces, Tom Naughton (UCL Cancer Institute) introduces the complex world of chronobiology and circadian rhythms.
Mark Stewart shares his group’s work on developing an appropriate small animal model for SUDEP, a condition that presents a significant challenge to researchers, particularly given that it occurs rarely and under circumstances where physiological data are seldom available
Autoantibodies occur in many different nervous system disorders, and are increasingly being found in disorders not traditionally associated with the immune system. Determining if the autoantibodies play a functional or pathogenic role is critical in selecting the most appropriate treatment options.
Milan Fiala and Matteo Pellegrini review current research that indicates a role for omega-3 fatty acids in slowing the progression of mild cognitive impairment.
Researchers at Colombia University, New York (NY, USA), have recently demonstrated that tau pathology induces dysfunction in cells specifically tuned to compute spatial information.
Dr Paul Gallagher (Institute of Neurological Sciences, Glasgow, UK) provides an overview of these two recent papers by Jokubaitis and colleagues  and Cree and colleagues, which both assessed factors predictive of long-term disability outcomes in people with multiple sclerosis (MS).
A systemic immune network involving benign autoimmune T cells supports brain maintenance, function and repair, and could be boosted in a well-controlled manner for therapy of brain pathologies.