Latest News
Spinal cord stimulation and physical therapy have been reported to help a man, paralyzed since 2013, regain his ability to stand and walk with assistance.
In this week’s round-up, we cover the latest industry news from the US FDA and the halt of an Alzheimer’s drug following a toxic reaction.
Scientists have discovered a vicious feedback loop underlying brain degeneration in Alzheimer’s, which may explain why many drug trials have failed.
Journal Articles
In this research article from Journal of Comparative Effectiveness Research, a new network meta-analysis compares lurasidone and brexpiprazole in acute schizophrenia.
In this research article from Pain Management, researchers investigate the effects of pregabalin, gabapentin and gastroretentive gabapentin on simulated driving performance.
This research article from Neurodegenerative Disease Management investigates how age and disease duration affects Parkinson’s treatment outcome with levodopa-carbidopa intestinal gel.
Autoimmune
Could hyaluronic acid contribute to chronic white matter injury?
Can living in a sunnier climate in your youth reduce the risk of MS?
Cerebrovascular disease
Tissue clearing and imaging: an interview with early career researcher, Marika Ruiyao Cai
Investigational gene therapy licensed for Parkinson’s disease: industry news round-up
CNS/PNS/SNS
Pluripotent stem cell-derived neural cells show promise in spinal cord repair
Spinal cord injuries could be repaired by stem cell-based therapy
Cognitive/neurodegenerative disorders
Alzheimer’s drug development halted following toxic reaction: industry news round-up
Why do so many clinical trials for Alzheimer’s fail? New discovery sheds light
From risk to resilience: understanding the role of genetics in Alzheimer’s disease
Demyelinating disease
Landmark simvastatin trial for secondary progressive multiple sclerosis begins in the UK
Ibudilast decreases progression of brain atrophy in progressive multiple sclerosis
Myelocortical multiple sclerosis: has a novel subtype been identified?
Development and pediatrics
Cerebral organoids and brain development: how do we define cell maturity?
Autism and insecticides: could maternal exposure increase risk in offspring?
NICE issues draft guidance against Spinraza® for spinal muscular atrophy
Epilepsy and seizure
First FDA-approved cannabinoid-derived drug for seizures
Epilepsy and cannabinoids: current consensus, controversies and future outlook
Reports of brain damage call a halt to Bellicum trials: industry news round-up
Genetics
From risk to resilience: understanding the role of genetics in Alzheimer’s disease
Build-up of RNA-binding proteins found in individuals with ALS and dementia
Personalized neurological fingerprint could increase effectiveness of Alzheimer’s treatment
Headache
Alzheimer’s drug development halted following toxic reaction: industry news round-up
Aimovig® receives EMA license for the prevention of migraine
Aimovig® receives positive CHMP opinion for the prevention of migraine
Immune disorders and inflammation
Inflammatory disease and anxiety: could endocannabinoids be a mechanism of comorbidity?
FENS 2018: Immune system offers new way of treating Alzheimer’s disease
FENS 2018: Could anxiety and inflammation be treated with cannabis?
Infection
Zika vaccine yields promising results for treating glioblastoma
Injury/trauma
Movement disorders
BrainStorm scraps initial access to NurOwn® for amyotrophic lateral sclerosis
Neuro-ophthalmology
Vision in Alzheimer's disease: a focus on the anterior afferent pathway
Glaucoma research gives a glimpse of a novel neuroprotection mechanism
Neurometabolic
Epigenetics, opioids and immune regulation: interviews from SfN17
Jeffrey Iliff: glymphatics, Alzheimer’s and future directions
SfN17: Neurodegeneration and the microbiome – new research highlights
Neuromuscular
New genetic suspects identified for ALS and FTD
Novel discovery in motor neuron disease may pave the way for future treatments
EAN 2017: Guillain-Barré syndrome risk associated with month of birth
Neuropsychiatry
Autism and insecticides: could maternal exposure increase risk in offspring?
Inflammatory disease and anxiety: could endocannabinoids be a mechanism of comorbidity?
Oncology/tumor
Zika vaccine yields promising results for treating glioblastoma
Brain cancer dataset made freely accessible to global researchers
Brain metastases could be tackled using new therapy with silibinin
Pain
Spinal cord stimulation enables paralyzed man to walk
Chronic pain relief: medical marijuana study identifies possible change in brain connections
NCTalks with Irene Tracey: lessons from pain, analgesia and anesthesia
Sleep
#NCIntroduces... Sleep science
Better sleep works like a dream at reducing fear learning
Sleep research realizes the dream of understanding brain plasticity mechanisms
