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Organoids
0Organoids: grow your own brain

Jenny Straiton explores the miniature world of organoids and discusses how these small models are making big changes in the world of neurological research.

Autoimmune

Could hyaluronic acid contribute to chronic white matter injury?

Can living in a sunnier climate in your youth reduce the risk of MS?

Could transcranial direct current stimulation offer relief from fatigue in multiple sclerosis sufferers?

Cerebrovascular disease

Hypertension drug increases cerebral blood flow in people with Alzheimer’s, study suggests

Regenerative stroke therapies: an interview with Steven Cramer

Stroke recovery: could the microbiome be a new therapeutic option?

CNS/PNS/SNS

New technology generates synthetic speech using brain activity

Cerebral organoids: scientists grow ‘mini-brains’ that can contract muscle

Does ‘broken heart’ syndrome originate in the brain?

Cognitive/neurodegenerative disorders

Risk of dementia may be increased with certain anticholinergics, study suggests

Hypertension drug increases cerebral blood flow in people with Alzheimer’s, study suggests

Late-life Alzheimer’s pathology may be predicted with sleep history

Demyelinating disease

Multiple sclerosis: determining the dynamic nature of oligodendrocyte regeneration

Biomarker discovery and development in multiple sclerosis: where are we now?

US FDA warns of stroke risk with multiple sclerosis drug: industry news round-up

Development and pediatrics

Is exercise the newest way to re-tune brain structure in mice with autism spectrum disorder?

Autism linked to mutations in ‘junk’ DNA and not specific genes, study reveals

Brain organoids: defining maturity, addressing the challenges and exploring future directions

Epilepsy and seizure

WHO releases first global report on epilepsy

tRNAs: a blood-based biomarker for predicting seizures?

Children’s brains remap and retain visual perception after surgery for severe epilepsy

Genetics

Early-onset Alzheimer’s disease linked to high LDL cholesterol levels

Autism linked to mutations in ‘junk’ DNA and not specific genes, study reveals

Ask the Experts: Gene therapies in neurological diseases (Part II: challenges and future outlooks)

Headache

Why are migraines more common in women? New sex-specific insights revealed

US FDA warns of stroke risk with multiple sclerosis drug: industry news round-up

Alzheimer’s drug development halted following toxic reaction: industry news round-up

Immune disorders and inflammation

Inflammatory disease and anxiety: could endocannabinoids be a mechanism of comorbidity?

FENS 2018: Immune system offers new way of treating Alzheimer’s disease

FENS 2018: Could anxiety and inflammation be treated with cannabis?

Infection

Could a bacterial polysaccharide suppress fatal brain inflammation?

Link between Alzheimer’s disease and periodontal bacteria gains traction

ANA 2018: key highlights and news stories

Injury/trauma

Could concussion symptoms in mice be reversed by magnetic therapy?

Tau biomarker linked to chronic traumatic encephalopathy in former athletes

New technology generates synthetic speech using brain activity

Movement disorders

Study reveals possible early signs of Parkinson’s in the brain

Stem cell therapies for Parkinson’s disease: current status and future perspectives

Could a noninvasive biomarker for Parkinson’s disease lie in EEG data?

Neuro-ophthalmology

Gene therapy breakthrough allows mice to regain sight

Could an eye scan detect signs of Alzheimer's disease?

Vision in Alzheimer's disease: a focus on the anterior afferent pathway

Neurometabolic

Epigenetics, opioids and immune regulation: interviews from SfN17

Jeffrey Iliff: glymphatics, Alzheimer’s and future directions

SfN17: Neurodegeneration and the microbiome – new research highlights

Neuromuscular

New genetic suspects identified for ALS and FTD

Novel discovery in motor neuron disease may pave the way for future treatments

EAN 2017: Guillain-Barré syndrome risk associated with month of birth

Neuropsychiatry

Addiction: a compulsive interplay between drugs, cues and habits

Galanin identified as new therapeutic target for the treatment of depression

Brain ‘fingerprinting’: a whole-system perspective into psychiatric conditions

Oncology/tumor

Depatux-M fails to meet primary endpoint in late-stage trial for newly diagnosed glioblastoma

CAR T-cell therapy: what are the neurological side effects?

SurVaxM for newly diagnosed glioblastoma: an interview with Manmeet Ahluwalia

Pain

Why are migraines more common in women? New sex-specific insights revealed

Could neuropathic pain be treated by modulation of immune cells?

New smartphone application could detect first signs of opioid overdose

Sleep

Late-life Alzheimer’s pathology may be predicted with sleep history

Can night owls ‘retrain’ their body clocks to improve mental wellbeing and performance?

Tau accumulation in the brain may be linked to sleep apnea