Latest News
A collaboration of researchers from across the USA has uncovered two closely related cytokines that may help explain why certain patients develop progressive multiple sclerosis, the most severe form of the disease.
Researchers have developed a 3D, all-human, in vitro model to help overcome challenges in delivering drugs to the brain.
Identification of loci associated with risk of Parkinson’s disease adds to understanding of genetic factors contributing to development of the disease
Journal Articles
This article examines physicochemical and cell-based assays and in vitro studies that have assessed the antioxidant properties of multitarget compounds.
In this review, the authors discuss the challenges associated with neural regeneration and review the progress of stem cell-based regenerative medicine.
Preliminary findings suggest that some cell therapies may be relatively safe and effective, but larger double-blinded placebo-controlled studies are needed to establish the long-term risks and benefits.
Autoimmune
Multiple sclerosis research suggests a neuroprotective benefit following resistance training
Parkinson’s is partly an autoimmune disease, new study states
Autoantibodies in neurological disorders – a review from Judith Greer
Cerebrovascular disease
Inflammation in brain blood vessels leads to gastrointestinal failure
Blood protein biomarkers as diagnostic tool for ischemic stroke: a systematic review
CNS/PNS/SNS
Novel blood–brain barrier model looks to shake-up drug delivery research
Muscle-derived stem cells in peripheral nerve regeneration: reality or illusion?
Cognitive/neurodegenerative disorders
Progressive multiple sclerosis marker uncovered in mouse study
Ask the Experts: the genetics of Alzheimer’s disease (Part 3: Looking ahead)
Demyelinating disease
Progressive multiple sclerosis marker uncovered in mouse study
Gut bacteria influence multiple sclerosis onset and progression
Multiple sclerosis drug trials: Luciano Rossetti on the recent cladribine approval
Development and pediatrics
Infographic: The facts about Zika
Epilepsy and seizure
Epileptic brain activity found in transgenic mouse lines
Technological advances in pediatric epilepsy surgery: implications for tuberous sclerosis complex
Genetics
Ask the Experts: the genetics of Alzheimer’s disease (Part 3: Looking ahead)
Ask the Experts: the genetics of Alzheimer’s disease (Part 1: Introduction to Alzheimer’s genetics)
Headache
Chronic migraine: new data shows Botox has more favorable tolerability than Topamax
EAN 2017: Monoclonal antibody could be an effective treatment for chronic migraine
Immune disorders and inflammation
Gut bacteria influence multiple sclerosis onset and progression
Inflammation in brain blood vessels leads to gastrointestinal failure
EAN 2017: Guillain-Barré syndrome risk associated with month of birth
Infection
Infographic: The facts about Zika
Zika virus update: a note from the Editor
What can climate-driven models teach us about the Zika outbreak?
Injury/trauma
Brain differences observed in contacts sport athletes
'Should we retire the term concussion?': live debate from Frontiers in TBI
TBI, animal models and neuroimaging: David Brody at Frontiers in TBI
Movement disorders
Progressive multiple sclerosis marker uncovered in mouse study
New genetic risk variants for Parkinson’s disease discovered
Gut bacteria influence multiple sclerosis onset and progression
Neuro-ophthalmology
Management of glaucoma as a neurodegenerative disease
Genetic analysis identifies loci associated with macular telangiectasia type 2
The best of 2016 on Neurology Central – a note from the Editor
Neurometabolic
Could the gut microbiome hold the key to neurodegenerative disorders?
The best of 2016 on Neurology Central – a note from the Editor
Energy drinks and alcohol may affect adolescent brains in similar way to cocaine
Neuromuscular
Novel discovery in motor neuron disease may pave the way for future treatments
EAN 2017: Guillain-Barré syndrome risk associated with month of birth
Neuropsychiatry
Effects of long-term schizophrenia medication use unraveled in new study
Inflammation in brain blood vessels leads to gastrointestinal failure
Honing in on hormone-sensitive neural targets for therapeutic intervention: mission impossible?
Oncology/tumor
Novel drug target identified for glioblastoma treatment
Role of cellular prion protein in neurofibromatosis 2 tumor development uncovered
Alzheimer’s disease patients may have a lower risk of developing lung cancer
Pain
Tracking opioid misuse using Twitter
EAN 2017: Monoclonal antibody could be an effective treatment for chronic migraine
Sleep
Alzheimer’s and sleep: an interview with Ram Sharma
Poor sleep quality associated with presence of Alzheimer’s disease biomarkers
Light, sleep and circadian rhythms in older adults with Alzheimer's disease and related dementias