Latest News
In a new case series of 177 players, diagnosis rate is highest recorded to-date.
A collection of news highlights from AAIC held in London, UK, 16–20 July 2017.
The Lancet International Commission on Dementia Prevention, Intervention and Care has reported that more than one-third of global dementia cases may be preventable through addressing lifestyle factors that impact an individual’s risk.
Journal Articles
The goal of this study was to test the state of methylation of transcription start positions in DNA that are actively involved in transcription.
This study generates a novel dataset of associations for disorders such as major depression and schizophrenia, providing a global perspective for their genetic etiology.
This Review looks at the literature surrounding recent neurophysiological techniques and novel surgical tools in pediatric epilepsy.
Autoimmune
Parkinson’s is partly an autoimmune disease, new study states
Autoantibodies in neurological disorders – a review from Judith Greer
Cerebrovascular disease
CNS/PNS/SNS
Q&A follow-up: Drugs and Driving: Discussing the cognitive effects of drugs on driving performance
New cerebrospinal fluid biomarkers in Alzheimer’s disease
EAN 2017: Guillain-Barré syndrome risk associated with month of birth
Cognitive/neurodegenerative disorders
High prevalence of CTE observed in deceased American football players
NCTalks at AAIC 2017: Megan Zuelsdorff on lifetime stress, racial disparities and cognitive health
NCTalks at AAIC 2017: Kim Mueller on speech decline as a marker for MCI
Demyelinating disease
Human herpes virus 6 may hamper the brain's ability to repair damaged cells
Development and pediatrics
DNA methylation and transcription onset in the brain
Small-molecule BDNF mimetic may improve symptoms of Rett syndrome
Technological advances in pediatric epilepsy surgery: implications for tuberous sclerosis complex
Epilepsy and seizure
Technological advances in pediatric epilepsy surgery: implications for tuberous sclerosis complex
Epilepsy drug receives approval as monotherapy from European Medicines Agency
Genetics
NCTalks at AAIC 2017: Julie Williams on Alzheimer’s genetics
DNA methylation and transcription onset in the brain
Small-molecule BDNF mimetic may improve symptoms of Rett syndrome
Headache
EAN 2017: Monoclonal antibody could be an effective treatment for chronic migraine
EAN 2017: Cannabinoids suitable for migraine prophylaxis
Noninvasive brain stimulation: an interview with Eric Wasserman
Immune disorders and inflammation
EAN 2017: Guillain-Barré syndrome risk associated with month of birth
Parkinson’s is partly an autoimmune disease, new study states
Infection
NS1-based Zika vaccine demonstrates promise in mice
Zika virus to be investigated as novel glioblastoma treatment
Injury/trauma
High prevalence of CTE observed in deceased American football players
Novel inflammatory biomarkers could lead to an effective diagnostic test for TBI
Movement disorders
NCTalks with Jerrold Vitek: Parkinson's, neuromodulation and collaboration
Parkinson’s disease: asparagine endopeptidase as a potential drug target
EAN 2017: Guillain-Barré syndrome risk associated with month of birth
Neuro-ophthalmology
Management of glaucoma as a neurodegenerative disease
Genetic analysis identifies loci associated with macular telangiectasia type 2
The best of 2016 on Neurology Central – a note from the Editor
Neurometabolic
Could the gut microbiome hold the key to neurodegenerative disorders?
The best of 2016 on Neurology Central – a note from the Editor
Energy drinks and alcohol may affect adolescent brains in similar way to cocaine
Neuromuscular
EAN 2017: Guillain-Barré syndrome risk associated with month of birth
Neuropsychiatry
NCTalks at AAIC 2017: Megan Zuelsdorff on lifetime stress, racial disparities and cognitive health
Neurotransmitter receptor genotypes associated with mental and behavioral disorders
Is a polygenic predictor of antidepressant response a possibility?
Oncology/tumor
Role of cellular prion protein in neurofibromatosis 2 tumor development uncovered
Alzheimer’s disease patients may have a lower risk of developing lung cancer
Neuroblastoma detected by novel biomarker assay with increased sensitivity
Pain
EAN 2017: Monoclonal antibody could be an effective treatment for chronic migraine
EAN 2017: Cannabinoids suitable for migraine prophylaxis
Recent advances in spinal cord stimulation for pain treatment
Sleep
Poor sleep quality associated with presence of Alzheimer’s disease biomarkers
Light, sleep and circadian rhythms in older adults with Alzheimer's disease and related dementias
#NCintroduces… Mammalian chronobiology and circadian rhythms