Latest News
Researchers have found the first evidence that autoimmunity plays a role in Parkinson’s disease, showing that T cells recognize α-synuclein peptides.
An international research team have shown that gene editing reverses Huntington’s symptoms without off-target effects in a mouse model.
Anthranilic acid is associated with greater risk of dementia, along with other kynurenine pathway metabolites.
Journal Articles
The hypothesis that antidepressant response has a relevant genetic component was initially suggested by the observation that this phenotype clusters in families.
This review explores the limitations of the present technology and current challenges of SCS before reviewing some of the most important recent advances.
This article summarizes the results of brain stimulation in HD and gives a perspective on the therapeutic role for neuromodulatory brain stimulation methods.
Autoimmune
Parkinson’s is partly an autoimmune disease, new study states
Autoantibodies in neurological disorders – a review from Judith Greer
Cerebrovascular disease
Spider venom affords neuroprotection after stroke
Orthostatic hypotension could contribute to risk of dementia
CNS/PNS/SNS
Brain stimulation may not be beneficial to cognitive training
Long-term opioid therapy may increase the risk of adverse outcomes in polyneuropathy patients
Spinal muscular atrophy may be caused by synaptic abnormalities
Cognitive/neurodegenerative disorders
Parkinson’s is partly an autoimmune disease, new study states
Huntington’s pathology alleviated by CRISPR/Cas9 gene editing
Demyelinating disease
World MS Day on Neuro Central – note from the Editor
New research takes us a step forward in the fight to understanding multiple sclerosis
Development and pediatrics
Early brain development and cognitive aging – a global challenge
NS1-based Zika vaccine demonstrates promise in mice
Spinal muscular atrophy may be caused by synaptic abnormalities
Epilepsy and seizure
Epilepsy drug receives approval as monotherapy from European Medicines Agency
Scientists discover ‘silent seizures’ in Alzheimer’s disease patients
Genetics
Huntington’s pathology alleviated by CRISPR/Cas9 gene editing
Headache
Noninvasive brain stimulation: an interview with Eric Wasserman
Electrical stimulation could provide pain relief alternative for migraines
Psychological mislabeling of chronic pain: lessons from migraine in the 20th century
Immune disorders and inflammation
Parkinson’s is partly an autoimmune disease, new study states
Autoantibodies in neurological disorders – a review from Judith Greer
Infection
NS1-based Zika vaccine demonstrates promise in mice
Zika virus to be investigated as novel glioblastoma treatment
Injury/trauma
Stem cell therapy for spinal cord injury: the latest updates from #TalkingRegMed
Strategic brain training could stimulate neural plasticity years after a traumatic brain injury
NCTalks at AAN 2017: Michael Alosco on CTE and the search for an in vivo diagnosis
Movement disorders
Parkinson’s is partly an autoimmune disease, new study states
Huntington’s pathology alleviated by CRISPR/Cas9 gene editing
Neuro-ophthalmology
Management of glaucoma as a neurodegenerative disease
Genetic analysis identifies loci associated with macular telangiectasia type 2
The best of 2016 on Neurology Central – a note from the Editor
Neurometabolic
Could the gut microbiome hold the key to neurodegenerative disorders?
The best of 2016 on Neurology Central – a note from the Editor
Energy drinks and alcohol may affect adolescent brains in similar way to cocaine
Neuromuscular
Repurposing of malaria drug to halt ALS disease progression
World MS Day on Neuro Central – note from the Editor
Spinal muscular atrophy may be caused by synaptic abnormalities
Neuropsychiatry
Is a polygenic predictor of antidepressant response a possibility?
Daniel Blumberger on rTMS: successes, hurdles and what the future may hold
Clinicians’ perceptions of pharmacogenomics use in psychiatry
Oncology/tumor
Review of stereotactic radiosurgery for intradural spine tumors
Immunotherapy and targeted therapy in brain metastases: emerging options in precision medicine
Pain
Recent advances in spinal cord stimulation for pain treatment
Chronic pain linked to memory decline and dementia in new study
Long-term opioid therapy may increase the risk of adverse outcomes in polyneuropathy patients
Sleep
Light, sleep and circadian rhythms in older adults with Alzheimer's disease and related dementias
#NCintroduces… Mammalian chronobiology and circadian rhythms