A rat’s guide to virtual reality

Written by Ryan Gilroy (Future Science Group)

Testing rats in a virtual reality (VR) maze uncovers a specific neural mechanism behind navigation, offering an insight into the pathogenesis of neurodegenerative diseases.  

In a recent study, senior author Mayank Mehta and his team from the University of California, Los Angeles (UCLA; CA, USA) monitored dorsal CA1 neuronal activity in the hippocampus of rats while the animals navigated a maze in VR. By developing our understanding of the underlying neural circuitry, this study paves the way for treating hippocampus dysfunctionrelated neurological disorders including Alzheimer’s, schizophrenia, and epilepsy. 

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